Publications by authors named "A J Tajik"

Cardiovascular complications of Brucellosis are not common and affecting less than 2% of cases. In clinical practice, endocarditis is the most frequent cardiovascular complication and is responsible for most of the brucellosis-related mortality cases and usually diagnosed lately in the course of the disease with mostly aorta valve involvement. In this case report, we present the case of a 27-year-old woman who was admitted to the hospital with fever, sudden onset right side hemiparesis, and horizontal gaze palsy.

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Objectives: This study aims to investigate the availability, affordability, and accessibility of antidiabetic medications in Herat, Afghanistan, in 2023.

Methods: Adhering to WHO and HAI guidelines, a systematic survey approach was utilized to collect data on the pricing, availability, and affordability of commonly prescribed antidiabetic medications. Data collection spanned a month and involved four investigators using a standardized template.

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Article Synopsis
  • Brain metastases (BMs) are the most common and lethal brain tumors, primarily originating from lung adenocarcinoma (LUAD), yet reliable predictors for their development are currently lacking.
  • Researchers analyzed 402 tumor and plasma samples from LUAD patients to create a predictive model based on DNA methylation signatures, combining it with clinical data for personalized risk assessments of developing BMs.
  • The study also identified unique genetic markers and immune cell changes that could aid in early detection of BMs through non-invasive tests, enhancing the potential for targeted and effective treatments.
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Hypertrophic cardiomyopathy is the most common inherited cardiac disease, exhibiting diverse phenotypes. Obstructive hypertrophic cardiomyopathy occurs in about two-thirds of cases and carries a worse prognosis. Mavacamten use in heart transplant recipients is limited.

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