Publications by authors named "A J Sutton"
Objective: This systematic search and review aimed to evaluate the available literature on discontinuation of adalimumab and other tumor necrosis factor inhibitors (TNFi) for patients with well-controlled chronic inflammatory arthritides.
Methods: We conducted a publication search on adalimumab discontinuation from 2000-2023 using PubMed, CINAHL, EMBASE, and Cochrane Library. Included studies evaluated adalimumab discontinuation approaches, tapering schemes, and outcomes including successful discontinuation and recapture after flare, in patients with well-controlled disease.
The Cohesion Theory of the ascent of water in trees is a quiet triumph of modern science. Besides hydrodynamics, the physics of transpiration involves capillarity, evaporation and osmosis - phenomena which all have a history of considerable theoretical confusion. The aim of this paper is to supplement existing accounts of this physics in the plant science literature.
View Article and Find Full Text PDFThis Letter reports a search for charge-parity (CP) symmetry violating nonstandard interactions (NSI) of neutrinos with matter using the NOvA Experiment, and examines their effects on the determination of the standard oscillation parameters. Data from ν_{μ}(ν[over ¯]_{μ})→ν_{μ}(ν[over ¯]_{μ}) and ν_{μ}(ν[over ¯]_{μ})→ν_{e}(ν[over ¯]_{e}) oscillation channels are used to measure the effect of the NSI parameters ϵ_{eμ} and ϵ_{eτ}. With 90% CL the magnitudes of the NSI couplings are constrained to be |ϵ_{eμ}|≲0.
View Article and Find Full Text PDFArticle Synopsis
- The development of lichen planus (LP) from radiation is very rare, with only 14 cases noted, and malignancy linked to LP is uncommon, primarily seen in oral forms.
- This report discusses a unique case of erosive cutaneous LP that transformed into malignancy at a site previously treated with radiation, highlighting the need for careful evaluation and monitoring in similar cases.
Article Synopsis
- Thumb carpometacarpal osteoarthritis (CMC-1 OA) is a common issue especially in older adults and women, and there's an increasing need for effective non-surgical treatment options as its prevalence rises.
- Previous research included two network meta-analyses on nonoperative interventions for CMC-1 OA but only focused on specific methods (splints and intraarticular injections), highlighting the gap for a comprehensive comparison.
- The study aimed to evaluate the effectiveness of various nonoperative treatments for CMC-1 OA by analyzing pain relief, functional improvement, and grip strength through a systematic review of 29 studies, ultimately including 22 trials for detailed comparison.