Publications by authors named "A J Sogaard"

Article Synopsis
  • * The study introduces enhanced modeling techniques for neutrino flux and detector response, and it distinguishes between starting (inside) and throughgoing (outside) neutrino interaction events to improve energy resolution.
  • * The findings indicate a best-fit point for the 3+1 model with sin²(2θ_{24})=0.16 and Δm_{41}²=3.5 eV², supporting previous studies while showing consistency with no evidence of sterile neutrinos, as reflected
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Drug targeting is a methodology that helps to overcome the side effects of therapeutic molecules. However, insufficient targeting specificity and the on-target/off-site delivery leave much room for improvement in the targeting endeavors. One approach to enhance the specificity of drug targeting is to engineer artificial receptors with recognition ligands not observed in nature.

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  • - A study examined the occurrence of post-herpes simplex virus 1 encephalitis (HSE) NMDA receptor encephalitis (NMDARE) in Denmark, identifying cases from various databases and literature.
  • - Out of 44 HSE patients, 16 met the criteria for NMDARE, with only 9 confirmed cases of post-HSE NMDARE identified in Denmark from 2009 to 2021.
  • - The data revealed that while adult cases were mainly older and similar in clinical presentation to literature cases, the absence of reported pediatric cases raises concerns about underdiagnosis in this group.
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  • A study in Norway found that individuals with lower educational levels have a higher risk of hip fractures, particularly among those aged 50 to 90 years.
  • For men with primary education, the risk of hip fractures was significantly higher compared to those with tertiary education, while women showed similar trends.
  • Interestingly, for individuals over 90 years old, the cumulative incidence of hip fractures was higher in those with higher education due to increased life expectancy, reversing the trend seen in younger age groups.
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The design of artificial, synthetic cells is a fundamentally important and fast-developing field of science. Of the diverse attributes of cellular life, artificial transmembrane signaling across the biomolecular barriers remains a high challenge with only a few documented successes. Herein, the study achieves signaling across lipid bilayers and connects an exofacial enzymatic receptor activation to an intracellular biochemical catalytic response using an artificial receptor.

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