Raman spectroscopy of ovarian and peritoneal tissue in the assessment of ovarian cancer.

During post chemotherapy surgery for ovarian cancer, it is important to ensure that any residual disease is carefully assessed and removed. The assessment remains subjective, despite clear evidence of the benefits of complete macroscopic resection. In this work, we have considered Raman spectroscopy as a possible tool for residual disease assessment by exploring its ability to correctly classify ovarian cancer from benign and borderline tissues.

Longitudinal Study on Clinical Predictors for Allergic Bronchopulmonary Aspergillosis in Children and Young People with Cystic Fibrosis Highlights the Impact of Infection with and and Ivacaftor Treatment.

Allergic bronchopulmonary aspergillosis (ABPA) is a well-known complication in children and young people with cystic fibrosis (CF) and without treatment causes structural lung damage. We performed a longitudinal observational study to identify clinical risk factors for ABPA in a cohort of children and young people with CF aged 8 to 17 years at baseline. Anonymised annual review UK CF Registry data from 2009 to 2019 for patients aged 8-17 years in 2009 were collected, with lung transplant recipients excluded.

Organogermanium: Potential beneficial effects on the cardiovascular system.

Organogermanium, especially poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132), has been known to enhance immune-modulatory activities. However, the in vivo and in vitro evidence accumulated over the last 20 years reveals that Ge-132 has unique but underappreciated multi-functional properties that have a potential positive effect for the cardiovascular system. A hydrolysate of Ge-132, monomeric 3-(trihydroxygermyl)propanoic acid, forms a complex with a vicinal diol structure (i.

Exploring environmental and managerial impacts of crude oil volatility on QUAD financial markets: Insights into dynamic connectedness.

The QUAD nations' (United States, India, Japan, and Australia) financial markets are deeply integrated with global markets. The burgeoning surge of risk in global markets requires caution, which can be possible by determining the connectedness. This study elucidates the dynamic connectedness between crude oil and the financial markets of QUAD nations, aiming to enhance understanding of its environmental and managerial implications.