Publications by authors named "A J Sempere"
There is no experience with ciprofloxacin for the treatment of carbapenemase-producing Gram-negative bacteria (CP-GNB) infections. This is a retrospective single-centre study where we describe the clinical evolution of all consecutive adult patients who received ciprofloxacin monotherapy for the treatment of CP-GNB infections. Primary outcomes were clinical failure (defined as death, lack of clinical improvement or a switch to another drug) at day 14 and 30-day all-cause mortality.
View Article and Find Full Text PDFBackground: We evaluated the microbial burden on gel polished nails (GPN), standard polished nails (SPN) and unpolished nails (UPN) before and after an alcohol-based hand rub (HHAB).
Methods: Three GPN, two SPN and five UPN in both hands were analyzed in 46 health-care workers volunteers. Nail length was maintained ≤2mm during the study.
Objective: To analyze the reliability of the estimated 1-repetition maximum (e1RM) through the repetition to fatigue method in 4 unilateral resistance training exercises performed using weight machines (ie, leg press, calf raises, leg extension, seated leg curl), and their relationship to gait-related tests.
Design: Cross-sectional study.
Setting: University sports complex.
Article Synopsis
- Study aimed to explore how common liver steatosis (LS) and liver fibrosis (LF) are among people with HIV, and what factors contribute to these liver conditions.
- In a large cohort study involving over 4,600 people, it was found that 28% showed signs of LS, with this prevalence increasing to 55% in a group with higher cardiovascular risk factors; LF was less common, affecting only about 1-5% across different assessment methods.
- Key factors linked to LS included current CD4 counts and conditions like diabetes and hypertension, while past use of certain HIV drugs was linked to LF; notably, current treatment with integrase strand transfer inhibitors appeared protective against LF.