Novel environmental variables help explain winter weather effects on activity and habitat selection of greater sage-grouse along the border of Colorado and Wyoming, USA.

For non-hibernating species within temperate climates, survival during severe winter weather often depends on individuals' behavioral response and available refugia. Identifying refugia habitat that sustains populations during adverse winter conditions can be difficult and complex. This study provides an example of how modeled, biologically relevant snow and weather information can help identify important relationships between habitat selection and dynamic winter landscapes using greater sage-grouse (Centrocercus urophasianus, hereafter "sage-grouse") as a model species.

Endogenous retroelement activation is implicated in IFN-α production and anti-CCP autoantibody generation in early Rheumatoid Arthritis.

Objectives: Endogenous retroelements (EREs) stimulate type 1 interferon (IFN-I) production but have not been explored as potential interferonogenic triggers in Rheumatoid Arthritis (RA). We investigated ERE expression in early RA (eRA), a period where IFN-I is increased.

Methods: ERE expression (LTR5, LINE1, SINE) in disease modifying treatment naïve eRA whole blood and bulk synovial tissue was examined by RT-PCR and Nanostring alongside IFN-α activity.

Deep phenotyping of T regulatory cells in psoriatic arthritis highlights targetable mechanisms of disease.

Regulatory T cells (Tregs) are immune regulatory T cells that are vital for controlling inflammation. The role of Tregs in inflammatory diseases namely Psoriatic Arthritis (PsA) is still poorly understood. The underlying reason being a lack of robust unbiased analysis to test the immune regulatory phenotype of human Tregs.

Taurine stimulation of planarian motility: a role for the dopamine receptor pathway.

Taurine, a normal dietary component that is found in many tissues, is considered important for a number of physiological processes. It is thought to play a particular role in eye development and in the maturation of both the muscular and nervous systems, leading to its suggested use as a therapeutic for Alzheimer's and Parkinson's diseases. Taurine increases metabolism and has also been touted as a weight loss aid.

The multifunctional use of an aqueous battery for a high capacity jellyfish robot.

The batteries that power untethered underwater vehicles (UUVs) serve a single purpose: to provide energy to electronics and motors; the more energy required, the bigger the robot must be to accommodate space for more energy storage. By choosing batteries composed primarily of liquid media [e.g.