Publications by authors named "A J Piraino"
Background: Despite the effectiveness of inhalation therapy, uncontrolled or severe asthma remains prevalent challenges in respiratory care Narrative Medicine (NM) offers a linguistic approach to comprehending illness experiences, thereby providing a framework for advancing healthcare.
Aim: The primary aim of this study was to gather narratives from individuals grappling with severe or uncontrolled asthma and their Healthcare Professionals (HCPs), in order to explore the intricate interplay among quality of care, quality of life, psychological and social determinants, and adherence patterns.
Methods: A cross-sectional NM study was conducted in Italy from February to December 2023, encompassing 135 patients with uncontrolled or severe asthma (54.
Article Synopsis
- - Psoriatic arthritis (PsA) is linked to high direct and indirect costs, primarily from medications, hospital stays, and work absenteeism; this study updated previous analyses on the economic aspects of PsA.
- - Out of 27 studies, it was found that biologic therapies, particularly bimekizumab and ixekizumab, showed better cost-effectiveness compared to non-biologic treatments for managing PsA.
- - Despite an increase in economic evaluations since the last review, PsA remains a significant economic burden globally, indicating a need for further studies to understand its financial impact better.
Article Synopsis
- The TRITRIAL study evaluated the fixed combination of beclometasone dipropionate/formoterol fumarate/glycopyrronium (BDP/FF/G) in patients with chronic obstructive pulmonary disease (COPD), focusing on patient-reported outcomes over 12 months.
- In a multicenter, prospective observational study with 655 patients, significant improvements were observed in health status (CAT scores), adherence to medication, quality of life, and sleep quality.
- The findings suggest that BDP/FF/G not only enhances the management of moderate-severe COPD but also improves overall patient well-being and reduces exacerbation rates.
In this article, we discuss the importance of real-world data in the treatment of patients with asthma and specifically the role of maintenance and reliever therapy (MART) with beclometasone dipropionate (BDP)/formoterol fumarate dihydrate (FF) delivered through a dry-powder inhaler (DPI) that contains an extrafine formulation. We also present the design of the NEWTON study. This multinational, multicenter, prospective, observational study will evaluate the real-world use of extrafine BDP/FF via a DPI as maintenance therapy and MART in patients with moderate to severe asthma.
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