Publications by authors named "A J Onuegbu"

Contrast enhanced pulmonary vein magnetic resonance angiography (PV CE-MRA) has value in atrial ablation pre-procedural planning. We aimed to provide high fidelity, ECG gated PV CE-MRA accelerated by variable density Cartesian sampling (VD-CASPR) with image navigator (iNAV) respiratory motion correction acquired in under 4 min. We describe its use in part during the global iodinated contrast shortage.

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Article Synopsis
  • Mitral annular calcification (MAC) increases the risk of cardiovascular issues and mortality, and this study examines its link to stroke risk over 15 years among a diverse group of participants.
  • In a cohort of 6,814 individuals, 9% had MAC at baseline, and during the follow-up period, 304 strokes occurred, predominantly ischemic.
  • After adjusting for various traditional risk factors, MAC was found to significantly predict all strokes and ischemic strokes, suggesting it should be considered in long-term stroke risk assessments.
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Background: Antiretroviral drugs are associated with adverse effects including chronic kidney disease. The onset of chronic kidney disease manifests with mild reduction in GFR. Early detection of chronic kidney disease is integral component of clinical medicine with major effect on disease labeling, intervention and drug dosing.

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Background: Arterial stiffness expressed by cardio-ankle vascular index (CAVI) is a marker of arteriosclerosis. It can increase vascular load, which in turn may affect the viscoelastic myocardial properties and the left ventricular compliance. In the present study, we sought to investigate the association between CAVI and left ventricular structure assessed by cardiac computed tomography (CT) in a multiethnic adult cohort.

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Coronary computed tomographic angiography (CCTA) may provide both anatomic and CT fractional flow reserve data (CTFFR). The objective is to use Bayesian analysis to develop a model wherein the probability of significant coronary artery disease (CAD) by CTFFR can be determined given the prior probability (P) of the combined clinical and CCTA result. 172 patients referred for CCTA and subsequently underwent coronary angiography were automatically referred to CTFFR analysis.

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