Publications by authors named "A J McCue"
Objective: To compare the impact of examination feedback versus access to historical examination questions on information retention.
Methods: First-year student-pharmacists completed a baseline knowledge assessment composed of 30 examination questions divided into three conditions of 10 questions each. In the CHEAT condition, students were provided with 10 questions and their correct answers ahead of time.
Vanadium redox flow batteries have applications for large-scale electricity storage. This paper reports the influence of carbon structural characteristics of sustainable walnut shell-derived carbons in carbon/polyvinylidene fluoride composite electrodes on vanadium redox reactions. Pyrolysis, gasification, and chemical treatment procedures were used to modify the structural characteristics of carbons.
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- T-cell engaging (TCE) bispecific antibodies can effectively target and eliminate cancer cells by activating T cells, but their use is limited by potential toxic side effects that can affect healthy cells as well.
- The study introduces a novel strategy using pro-drug forms of TCEs that become active specifically in the tumor environment by incorporating a masking approach that relies on tumor-enriched proteases.
- Researchers successfully engineered and tested a pro-drug TCE using the anti-CD3 antibody E10, demonstrating its ability to activate T cells selectively within tumors, highlighting a promising avenue for safer cancer immunotherapy.
The feasibility of producing activated carbon (AC) from real Household Mixed Plastic Waste (HMPW) comprising of LDPE, HDPE, PP, PS, and PET for carbon capture via direct carbonisation followed by microwave-assisted or conventional thermally assisted chemical activation was investigated. A microwave-assisted activation procedure was adopted to assess the impact on the CO capture capacity of the resulting AC using both a lower temperature (400 °C vs. 700 °C) and a shorter duration (5 vs.
View Article and Find Full Text PDFUnlabelled: Human immunodeficiency virus type 1 typically requires a high density of CD4 for efficient entry as a mechanism to target CD4+ T cells (T-tropic), with CCR5 being used most often as the coreceptor. When target T cells are limiting, the virus can evolve to infect cells with a low density of CD4 such as macrophages (M-tropic). The entry phenotype is known to be encoded in the viral Env protein on the surface of the virus particle.
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