Publications by authors named "A J Mackin"

Article Synopsis
  • A study looked at how often dogs have problems after getting blood transfusions, focusing on 858 dogs that received 1,542 transfusions from March to November 2022.
  • Out of the dogs, 8.9% experienced acute reactions when they got packed red blood cells, and 4.5% had reactions after receiving plasma products.
  • The study found that older stored blood and higher doses were linked to more reactions, so vets should pay attention to these factors when treating dogs.
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Article Synopsis
  • Management of immune thrombocytopenia (ITP) in dogs and cats lacks established evidence-based guidelines, leaving treatment decisions largely to clinician discretion.
  • The first-line treatment involves immunosuppressive glucocorticoids, with additional therapies such as azathioprine and vincristine used in more severe cases; however, optimal regimens are still unclear.
  • A consensus process involving a structured literature review and expert opinions led to the creation of guidelines highlighting the need for further research in ITP treatment options.
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Article Synopsis
  • Immune thrombocytopenia (ITP) is a prevalent acquired disorder affecting the blood clotting process primarily in dogs and less frequently in cats, leading to significant health risks in both species.
  • ITP can be classified into primary (autoimmune) and secondary (triggered by other diseases), but there is a lack of systematic evaluation regarding which underlying conditions trigger secondary ITP.
  • A comprehensive study developed guidelines through a structured review of literature, expert input, and consensus-building processes to create diagnostic algorithms and screening recommendations for ITP in dogs and cats.
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Purpose: To examine the efficacy and clinical characteristics of successful full-thickness macular hole closure with topical therapy.

Methods: Retrospective case series of full-thickness macular holes managed by a single retinal physician (DS) diagnosed and treated from 2017 to 22.

Results: Of 168 patients with full-thickness macular holes, 71 patients were started on steroid, carbonic anhydrase inhibitor, and nonsteroidal antiinflammatory (NSAID) drops.

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Background/purpose: To describe diagnostic characteristics and management of exudative macular detachment, a rare complication of pars plana vitrectomy and endolaser for diabetic vitreous hemorrhage.

Methods: Case report including multimodal imaging.

Results: Forty-seven-year-old man with diabetes mellitus Type 2 and proliferative diabetic retinopathy underwent uncomplicated 23-gauge pars plana vitrectomy, Triesence-assisted hyaloid peeling, fill-in endolaser, and intravitreal bevacizumab injection in the left eye for nonclearing visually significant vitreous hemorrhage.

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