Gestational organophosphate pesticide exposure and childhood cardiovascular outcomes.

Introduction: The general population is chronically exposed to organophosphate pesticides through various routes including ingestion, hand-to-mouth contact, inhalation, and dermal contact. Exposure to organophosphate pesticides during pregnancy impairs fetal development, but the potential long-term effects of gestational organophosphate pesticide exposure are less well understood.

Methods: We investigated associations between gestational organophosphate pesticide exposure and cardiovascular outcomes in 643 children in the Generation R Study, a prospective pregnancy cohort based in Rotterdam, The Netherlands.

Phenolization of the sinus tract in recurrent sacrococcygeal pilonidal sinus disease: long-term results of a prospective cohort study.

Aim: In recent years, the paradigm for the treatment of sacrococcygeal pilonidal sinus disease (SPSD) has shifted from surgical excision toward more minimally invasive techniques. Although extensive research has been conducted on the minimal invasive phenolization technique for primary SPSD, literature in recurrent SPSD is lacking. The purpose of this study was to report the long-term outcomes of the phenolization technique for recurrent SPSD.

Structural behaviour and construction of a monumental ice structure.

This paper investigates the use of ice-based materials combined with Fiber-Reinforced Polymer (FRP) to enhance the bending capacity of ice sculptures. Through three-point bending tests and ABAQUS simulations, the study analyses the mechanical behaviour of GFRP and cellulose ice, both separately and together. The results show that FRP improves tensile resistance while cellulose ice adds mass and ductility.

Integrated assessment of simultaneous threshold exceedance of heat, air pollution and airborne allergenic pollen across Europe.

Background: Climate change is expected to elevate exposure to several environmental health risk factors, including extreme environmental temperatures, air pollution and airborne allergenic pollen. Given their interconnected effects on respiratory and cardiovascular diseases, it is crucial to evaluate these exposures simultaneously. Yet, comprehensive efforts to do so remain limited.