Publications by authors named "A J Landgren"

Background: The National Cancer Institute funds many large cohort studies that rely on self-reported cancer data requiring medical record validation. This is labor intensive, costly, and prone to underreporting or misreporting of cancer and disparity-related differential response. US population-based central cancer registries identify incident cancer within their catchment area, yielding all malignant neoplasms and benign brain and central nervous system tumors with standardized data fields.

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Objective: In this post hoc analysis of a previously published study, we compared cytokines and adipokine levels in women and men with psoriatic arthritis (PsA) at baseline (BL) and 6 months (M6) following a weight loss intervention.

Methods: Patients with PsA (n=41) between 25 and 75 years of age, with body mass index (BMI)≥33 kg/m were included in a weight loss intervention with a very low energy diet (VLED) for 12 or 16 weeks depending on BL BMI<40 or ≥40 kg/m. As controls (n=39), obese individuals, already planned for VLED treatment were recruited and matched for sex, age and weight to the patients with PsA.

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  • The study compared health-related quality of life (HRQoL) among gout patients of different severity levels, focusing on overall impact and differences by sex.
  • Out of 1444 gout patients surveyed, about 54% responded, and the severity of gout was categorized based on the number of gout flares in the past year (mild, moderate, severe).
  • The results showed that patients with severe gout experienced significantly worse HRQoL scores compared to those with mild gout, indicating that the severity of gout flare-ups negatively affects both physical and mental well-being.
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  • Syphilis can cause membranous nephropathy, which is a condition that leads to nephrotic syndrome characterized by significant protein loss in urine.* -
  • A case study described a patient whose renal biopsy displayed a 'full house' immunohistochemical pattern, initially misdiagnosed and treated for other types of nephropathies.* -
  • After confirming syphilis and treating the patient with benzathine penicillin, the nephrotic syndrome resolved quickly, highlighting syphilis as an important but often overlooked cause of this condition.*
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