Publications by authors named "A J L Moore"
Members of the genus are well known for their medicinal properties, which can be attributed to their essential oils. In this work, we have examined the leaf essential oils of five understudied species collected from various locations in western North America. The essential oils were obtained by hydrodistillation and analyzed by gas chromatographic methods, including enantioselective gas chromatography.
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- This study focuses on PRT543, a new oral medication designed to inhibit PRMT5, an enzyme implicated in the growth of certain blood cancers.
- It specifically investigates the effects of PRT543 in patients suffering from advanced myeloid malignancies that have mutations in splicing factors, which are crucial for proper gene expression and can contribute to cancer progression.
- The early Phase Ib trial aims to assess the safety, tolerability, and initial effectiveness of PRT543 in these patients, providing groundwork for potential future treatments.
Despite 75% of people who experience a first episode of psychosis (FEP) reaching clinical remission, this population continue to face lower rates of vocational recovery. This review aimed to identify the factors which help and hinder individuals' employment and post-secondary education engagement post-FEP. Three electronic databases (Psych INFO, Medline and Social Science Database) were searched up to 21st August 2023.
View Article and Find Full Text PDFObjectives: While Colombians gained broad legal access to abortion in 2022, people still lack knowledge about its availability and face variable quality of care at health facilities. This study sought to understand whether online sellers provide the instructions and medication dosages necessary for effective medication abortions.
Design: The study design involved mystery clients contacting sellers identified across websites and social media platforms (Facebook, Instagram, and TikTok) to purchase abortion pills.