Publications by authors named "A J Korzekwa"

Bladder cancer is a very important issue in contemporary urology. The aim of this pilot study was to assess for the first time the clinical utility of semaphorin 3C (sema3C) and 4A (sema4A) in patients with non-muscle-invasive bladder cancer (NMIBC). The experiment involved 15 patients with NMIBC and 5 patients without malignancies as the control group.

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The incidence of bladder cancer worldwide in the last three decades has been increasing in both men and women. So far, there is no established non-invasive bladder cancer biomarker in daily clinical practice. Semaphorin 6D (sema6D) is a transmembrane protein that belongs to the class VI semaphorins.

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Article Synopsis
  • Researchers identified changes in 219 genes in Leydig cell tumors, but there's still limited understanding of their basic biochemical properties, highlighting the need for potential biochemical markers for better tumor management.
  • The study involved analyzing Leydig cell micronodules from azoospermic patients through histological staining and spectrophotometric measurements, focusing on proteins, carbohydrates, lipids, and nucleic acids.
  • Compared to healthy testis, Leydig cell tumors showed a significant loss of copper levels, which may be linked to their altered biochemical structure and could provide insights for new management strategies.
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There is a need to fully know the physiology of Eurasian beaver due to its essential role in environmental homeostasis. However, a "human factor" impacts this, including stress conditions and environmental pollution. Adrenal glands protect these all.

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