Is Patella Resurfacing Associated with Postoperative Extensor Mechanism Disruption After Total Knee Arthroplasty? A Systematic Review and Meta-Analysis.

Background: Patella resurfacing in total knee arthroplasty (TKA) involves surgical manipulation of the extensor mechanism, which can weaken or devascularize the patellar bone, quadriceps, and patellar tendon. Patella resurfacing may, in theory, increase the risk of postoperative extensor mechanism disruption (EMD).

Methods: We systematically searched the Cochrane, Embase, and PubMed databases to identify randomized controlled trials that reported the overall incidence of complications and surgery for EMD for resurfaced and unresurfaced patellae in patients who underwent primary TKA with a 2-year follow-up.

Cardiotoxicity of breast cancer drug treatments.

Breast cancer (BC) is a leading cause of cancer-related mortality among women worldwide. BC is regarded as a systemic disease. Consequently, the majority of BC patients undergo systemic therapy to reduce the risk of distant metastasis (DM) and associated mortality.

Time to loss of physical integrity of attractive targeted sugar bait (ATSB) stations in Western Province, Zambia: a survival analysis.

Background: Attractive targeted sugar baits (ATSBs) are a potential addition to an integrated vector management strategy against malaria. ATSB stations, which include a sugar bait and an ingestion toxicant, could potentially be deployed to attract-and-kill mosquitoes and thereby prevent malaria transmission. The physical durability of these stations is likely to be an important factor in decisions around future use strategies.

Racial differences in primary sclerosing cholangitis: A retrospective cohort study leveraging a new ICD-10 code.

Introduction And Objectives: There are limited data examining racial disparities in PSC-related clinical features and events. We aimed to leverage a new PSC ICD-10 code to characterize racial differences in a nationwide contemporary cohort of patients with PSC.

Patients And Methods: We used de-identified clinical/administrative data from the Vizient® Clinical Data Base to identify outpatient and inpatient adult patients with PSC using a PSC-specific ICD-10-CM code (K83.

Preserving the Biologically Coherent Generic Concept of , 'Plant Destroyer'.

is a long-established, well known and globally important genus of plant pathogens. Phylogenetic evidence has shown that the biologically distinct, obligate biotrophic downy mildews evolved from at least twice. Since, cladistically, this renders 'paraphyletic', it has been proposed that evolutionary clades be split into multiple genera (Runge et al.