Longitudinal association of statin treatment with insulin sensitivity and beta-cell function in the PROMISE cohort.

Context: Statin treatment lowers low-density lipoprotein (LDL) cholesterol thereby reducing cardiovascular risk. Meta-analyses of clinical trials report a higher risk of new-onset type 2 diabetes with statins. Current clinical evidence regarding effects of statins on insulin sensitivity and beta-cell function is limited.

Impact of an Antenatal Family-based Behavioral Treatment with a Nutrition and Exercise Lifestyle Intervention Program on Infant Weight-for-length at Birth.

Background: World Health Organization (WHO) growth standards, including weight-for-length, are used to monitor infant size. Excessive infant weight-for-length at or above the 85th percentile is a risk for childhood overweight. Although antenatal interventions like the nutrition and exercise lifestyle intervention program (NELIP) have successfully prevented excessive gestational weight gain, strategies to improve the intervention remain of interest.

Anishininew infant feeding experiences in Sandy Lake, Canada: a story of Waabeequanee.

Global public health recommendations for optimal infant nutrition include exclusive breastfeeding for the first 6 months of life. Breastfeeding has several benefits; however, breastfeeding initiation rates and duration remain below recommendations in Northwestern Ontario, Canada. Sandy Lake First Nation is particularly interested in understanding infant feeding experiences of community members to support increased breastfeeding initiation and duration.

Sustained Reduction of Subclinical Inflammation in the years after Breastfeeding.

Context: Lactation is associated with lower future risk of cardiovascular disease in women but the mechanism(s) underlying this relationship remain unclear.

Objective: We sought to characterize the relationship between duration of exclusive breastfeeding and cardiovascular risk factors over the first 5-years postpartum.

Design/setting/patients: In this prospective cohort study, 328 women underwent serial cardiometabolic characterization (anthropometry, blood pressure, lipids, fasting glucose, adiponectin, C-reactive protein (CRP)) at 1-year, 3-years, and 5-years postpartum.