An inhalation anaesthesia approach for neonatal mice allowing streamlined stereotactic injection in the brain.

Background: Investigating brain function requires tools and techniques to visualise, modify and manipulate neuronal tissue. One powerful and popular method is intracerebral injection of customised viruses, allowing expression of exogenous transgenes. This technique is a standard procedure for adult mice, and is used by laboratories worldwide.

Uses and abuses of the EEG in epilepsy.

Our purpose was to indicate clinical situations in epilepsy in which the EEG provides useful information and those in which it is unhelpful and should be avoided. We performed an overview of the formal evidence available through Medline, Cochrane, and the Internet, as well as a traditional review based on the questions commonly asked of the authors department in a London teaching hospital. We found that there is insufficient high-quality evidence to informed decisions regarding EEG utility.