Goldfish phenomics reveals commonalities and a lack of universality in the domestication process for ornamentation.

Domestication process effects are manifold, affecting genotype and phenotype, and assumed to be universal in animals by part of the scientific community. While mammals and birds have been thoroughly investigated, from taming to intensive selective breeding, fish domestication remains comparatively unstudied. The most widely bred and traded ornamental fish species worldwide, the goldfish, underwent the effect of long-term artificial selection on differing skeletal and soft tissue modules through ornamental domestication.

Childhood interstitial lung disease survivors in adulthood: a European collaborative study.

Background: Interstitial lung disease (ILD) is rarer in children (chILD) than adults, but with increasing diagnostic awareness, more cases are being discovered. chILD prognosis is often poor, but increasing numbers are now surviving into adulthood.

Aim: To characterize chILD-survivors and identify their impact on adult-ILD centers.

PytheasDB: An open-access graphical database of clinical data on rare pediatric digestive diseases.

Advances in genetic testing over the past decades are driving a continuing increase in the diagnosis and reporting of rare genetic diseases, but no tool has yet been developed to aggregate published molecular and phenotypic data, a task that is nevertheless essential to optimize patient care. In this article, we present PytheasDB, an online database of published clinical data from patients with rare digestive diseases. At the time of writing (August 2024), the database contains data from 833 patients with progressive familial intrahepatic cholestasis or trichohepatoenteric syndrome, collected from 172 articles.

Realizing the entanglement Hamiltonian of a topological quantum Hall system.

Topological quantum many-body systems are characterized by a hidden order encoded in the entanglement between their constituents. While entanglement is often quantified using the entanglement entropy, its full description relies on the entanglement Hamiltonian, which is commonly used to identify complex phases arising in numerical simulations, but whose measurement remains an outstanding challenge. Here, we map entanglement to spectral properties by realizing a physical system whose single-particle dynamics is governed by the entanglement Hamiltonian of a quantum Hall system.