Making Healthcare Decisions on Behalf of People in a Disorder of Consciousness. A "Risk-Making" Theory of Decisional Practices.

Healthcare decisions evaluate treatment risks and benefits, using a shared decision-making process between patient and clinician. Healthcare workers (HCWs) offer treatments based on condition specific evidence and expert knowledge. The patient evaluates treatment choices from their individual perception of how helpful or harmful treatment might be.

An optimized plasmalogen modulating dietary supplement provides greater protection in a male than female mouse model of dilated cardiomyopathy.

We previously reported that plasmalogens, a class of phospholipids, were decreased in a setting of dilated cardiomyopathy (DCM). Plasmalogen levels can be modulated via a dietary supplement called alkylglycerols (AG) which has demonstrated benefits in some disease settings. However, its therapeutic potential in DCM remained unknown.

"Nothing's changed, baby": How the mental health narratives of people with multiple and complex needs disrupt the recovery framework.

The dominant narrative in mental health policy and practice has shifted in the 21st century from one of chronic ill health to a 'recovery' orientation. Knowledge of recovery is based on narratives of people with lived experience of mental distress. However the narratives of people experiencing structural inequalities are under-represented in recovery research.

Friendship theory for public health research and practice: a critical realist review.

Aims: To critically analyse theories of friendship through privileging research on the experience of friendship among those who have experienced mental ill-health. To inform public health approaches that aim to facilitate friendship and assist those experiencing mental ill-health.

Method: A selective, iterative, purposive review of theoretical and empirical studies, within a critical realist epistemology, is undertaken to provide an analysis.