Publications by authors named "A J Dugas"

Article Synopsis
  • The study aimed to estimate the prevalence and trends of congenital eye anomalies (CEAs) in Paris from 2010 to 2020, analyzing data from all maternity units in the area.
  • Out of 115 identified cases of CEAs, the overall prevalence was 4.1 cases per 10,000 births, with 23.5% being prenatally diagnosed.
  • It was found that CEAs were commonly associated with other anomalies, as 20.9% had genetic issues, and 53% had additional extraocular anomalies, with a lower prenatal detection rate for isolated CEAs at only 13.3%.
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Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is a treatment option for peritoneal metastases (PM) but is associated with significant postoperative morbidity. The aim of this study was to determine the prognostic value of computed tomographic (CT)-measured sarcopenia on postoperative outcomes and survival in patients undergoing CRS-HIPEC for PM from various origins. A retrospective cohort study was conducted between 2012 and 2020.

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Background: Myelomeningocele (MMC) is a spinal cord congenital defect that leads to paraplegia, sphincter disorders and potential neurocognitive disabilities. Prenatal surgery of MMC provides a significant benefit compared to surgery at birth. Mesenchymal stromal cell (MSC) therapy as an adjuvant treatment for prenatal surgery showed promising results in animal experiments which could be considered for clinical use in human fetuses.

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