Publications by authors named "A J Dare"

Article Synopsis
  • Blueberries have a variety of anthocyanins that give them their blue color, and some types can produce more stable acylated anthocyanins, making them a focus for breeding.
  • This study focused on a specific gene, VcAAT1a, which was found to effectively produce different acylated anthocyanins in various plant systems.
  • The research identified that VcAAT1a only uses acetyl CoA as an acyl donor, and its promoter is activated by certain transcription factors, providing insight into how anthocyanin production is regulated in blueberries.
View Article and Find Full Text PDF

Background And Objectives: Prospective data on presentation and outcomes of colorectal cancer (CRC) in Nigeria are limited; however, emergency presentation with advanced disease is thought common.

Methods: Consecutive CRC patients presenting at six sites over 6 years were included. Risk factors for emergency presentation were evaluated using logistic regression methods.

View Article and Find Full Text PDF
Article Synopsis
  • - The study examines out-of-pocket costs for breast cancer treatment in Nigeria, highlighting that most patients face significant financial burdens, with a majority experiencing catastrophic health expenditures (CHE) due to the high costs of care.
  • - Data was gathered from 71 patients undergoing treatment, revealing that 78.9% to 100% experienced CHE, as their healthcare costs often exceeded 40% of their ability to pay or set income thresholds, and most patients lacked health insurance.
  • - The findings underscore the urgent need for policy changes to improve access to affordable cancer care in Nigeria, given that over 70% of patients at a major facility are financially strained by their treatment.
View Article and Find Full Text PDF

When surgical systems fail, there is the major collateral impact on patients, society and economies. While short-term impact on patient outcomes during periods of high system stress is easy to measure, the long-term repercussions of global crises are harder to quantify and require modelling studies with inherent uncertainty. When external stressors such as high-threat infectious disease, forced migration or climate-change-related events occur, there is a resulting surge in healthcare demand.

View Article and Find Full Text PDF

Purpose: The incidence of GI cancers is increasing in sub-Saharan African countries. We described the oncological care pathway and assessed presentation, diagnosis, and treatment intervals and delays among patients with GI cancer who presented to the Obafemi Awolowo University Teaching Hospitals Complex in Ile-Ife, Nigeria.

Methods: We analyzed data from 545 patients with GI cancer in the African Research Group for Oncology (ARGO) database.

View Article and Find Full Text PDF