An Analysis of the Food and Drug Administration Manufacturer and User Facility Device Experience Database for MAGnetic Expansion Control Spinal Rods.

Background: MAGnetic Expansion Control (MAGEC) rods can prevent repeated lengthening operations for scoliosis patients. However, there have been several Field Safety Notices issued, including a worldwide product recall due to actuator endcap separation. We aimed to review adverse events reported to the Food and Drug Administration (FDA) regarding MAGEC rods, focusing on MAGEC X.

Is MAGEC X better than earlier designs of magnetically controlled growing rod: an explant study.

Purpose: Determine the performance of MAGEC X rods through retrieval analysis and comparison with clinical data.

Methods: A multicentre explant database was searched to identify cases using MAGEC X device. Clinical and surgical data was gathered prospectively.

Imaging mass cytometry analysis of Becker muscular dystrophy muscle samples reveals different stages of muscle degeneration.

Becker muscular dystrophy (BMD) is characterised by fiber loss and expansion of fibrotic and adipose tissue. Several cells interact locally in what is known as the degenerative niche. We analysed muscle biopsies of controls and BMD patients at early, moderate and advanced stages of progression using Hyperion imaging mass cytometry (IMC) by labelling single sections with 17 markers identifying different components of the muscle.

Bracing Adolescent Idiopathic Scoliosis (BASIS) study - night-time versus full-time bracing in adolescent idiopathic scoliosis: study protocol for a multicentre, randomized controlled trial.

Aims: Scoliosis is a lateral curvature of the spine with associated rotation, often causing distress due to appearance. For some curves, there is good evidence to support the use of a spinal brace, worn for 20 to 24 hours a day to minimize the curve, making it as straight as possible during growth, preventing progression. Compliance can be poor due to appearance and comfort.

Explant analysis of a Discocerv cervical disc: A case study for a ceramic-on-ceramic cervical disc.

Explant analyses are key to better understanding the effectiveness of medical implants in replacing natural joints. For the first time, an explanted Discocerv cervical disc was examined. The implant utilised the articulation of a caudal zirconia cup (inferior component) and a cephalic alumina head (superior component).