The influence of age at total hip replacement on perioperative complications associated with a press-fit cementless stem with lateral bolt in dogs.

Objective: To assess the influence of age on perioperative stem-associated complications when total hip replacement (THR) was performed with a BFX lateral bolt stem.

Study Design: Retrospective (2017-2022).

Sample Population: A total of 197 client-owned dogs.

Medial versus lateral transcondylar screw placement for canine humeral intracondylar fissures: A randomized clinical trial.

Objective: To determine the influence of screw direction on complications following transcondylar screw placement for the treatment of canine humeral intracondylar fissures (HIFs).

Study Design: Equivalence, parallel group, randomized clinical trial.

Sample Population: Fifty-two client owned dogs (73 elbows).

Comparison of Hindlimb Conformation in Cats with and without Medial Patellar Luxation.

Objectives:  Medial patellar luxation (MPL) is the most common developmental cause of hindlimb lameness in cats. The association between femoral and tibial conformation and MPL measured on computed tomography (CT) has not been reported in cats. The aims were to report femoral and tibial conformation in cats with and without MPL and to report normal femoral and tibial angles.

Addition of elotuzumab to lenalidomide and dexamethasone for patients with newly diagnosed, transplantation ineligible multiple myeloma (ELOQUENT-1): an open-label, multicentre, randomised, phase 3 trial.

Background: Elotuzumab plus lenalidomide and dexamethasone has shown improved progression-free and overall survival versus lenalidomide and dexamethasone in patients with relapsed or refractory multiple myeloma. We aimed to assess these regimens in patients with newly diagnosed multiple myeloma who are ineligible for haematopoietic stem-cell transplantation (HSCT).

Methods: ELOQUENT-1 is an open-label, multicentre, randomised, phase 3 trial conducted at 185 hospitals, oncology practices, and research centres in 19 countries.