An unusual cause of a facial swelling.

This article discusses a rare cause of facial swelling secondary to an ectopic mandibular third molar and highlights the important of not overlooking plain radiographs when investigating facial swellings.

Using artificial intelligence to bring evidence-based medicine a step closer to making the individual difference.

The vision of evidence-based medicine is that of experienced clinicians systematically using the best research evidence to meet the individual patient's needs. This vision remains distant from clinical reality, as no complete methodology exists to apply objective, population-based research evidence to the needs of an individual real-world patient. We describe an approach, based on techniques from machine learning, to bridge this gap between evidence and individual patients in oncology.

Three-peaked chemiluminescent response of human peripheral blood leukocytes following stimulation with phytohaemagglutinin (PHA).

Luminol-enhanced chemiluminescence (CL) was used to examine the response of various leukocyte populations following stimulation with a crude extract of Phaseolus vulgaris, namely phytohaemagglutinin (PHA-C). Populations stimulated included a human peripheral mixed leukocyte preparation (MLP), and purified preparations of lymphocytes, monocytes and polymorphonuclear leukocytes (PMNL). Mouse peritoneal exudate cells and the lymphocytic cells lines Molt #4 and Daudi were also stimulated.

Routine clinical application of the lymphocyte fluorescence polarization test for malignant disease.

The technique of Lymphocyte Fluorescence Polarization (LFP) can confirm or exclude the presence of malignant disease. The results from tests on a total of 566 subjects showed a false-positive rate of 3.8% and a false-negative rate of 2.

Canine Dirofilaria immitis infection in a hyperenzootic area: examination by parasitologic findings at necropsy and by two serodiagnostic methods.

A total of 174 dogs from an area hyperenzootic for Dirofilaria immitis were grouped into 4 age categories and necropsied; information was obtained on adult D immitis infections and on the presence of microfilariae. Serum samples from these dogs were examined by an enzyme-linked immunosorbent assay (ELISA) for antibody to adult D immitis and by an indirect fluorescent antibody test (IFAT) for antibody to microfilarial surface antigens. In dogs less than or equal to 5 months of age, necropsy demonstrated no evidence of infection; however, positive serologic results indicated that some of these dogs had prepatent infections.