Publications by authors named "A J Arndt"

Objective: This study was to investigate alterations in contractile properties of the ankle plantar- and dorsiflexors in post-stroke individuals. The correlation between muscle architecture parameters and contractile properties was also evaluated.

Methods: Eight post-stroke individuals and eight age-matched healthy subjects participated in the study.

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Article Synopsis
  • * Twelve resistance-trained males participated in the jumps, with data collected on various stiffness measures during the eccentric phase, revealing strong correlations between the different methods used.
  • * Results indicate that the force plate-only method is valid for calculating stiffness and is comparable to 3D leg stiffness, which has implications for performance evaluation and injury risk assessment.
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Leopard sharks () are temperate, Eastern Pacific elasmobranchs popular in public aquariums. Blood analysis is commonly used for assessing animal health, yet reference values have not been established for this species. This study analyzed population data to characterize blood reference values for a collection of housed at a public aquarium.

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  • A case is reported involving a patient with advanced non-small cell lung adenocarcinoma who has been on crizotinib therapy and developed a new missense mutation in the ALK gene associated with resistance to this treatment.
  • The EML4/ALK translocation remained detectable despite the patient's cancer recurrence, and a 3D analysis suggested that the mutation contributes to crizotinib resistance while showing potential sensitivity to other drugs like brigatinib and lorlatinib.
  • The study emphasizes the effectiveness of combining preclinical and clinical approaches, including targeted sequencing and in vitro validation, which could enhance the use of molecular tumor boards in improving individualized cancer treatment strategies.
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Web-based interventions can be effective in treating depressive symptoms. Patients with risk not responding to treatment have been identified by early change patterns. This study aims to examine whether early changes are superior to baseline parameters in predicting long-term outcome.

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