Publications by authors named "A J Alessandri"

Electromagnetic actuation can support many fields of technology, such as robotics or biomedical applications. In this context, fully understanding the system behavior and proposing a low-cost package for feedback control is challenging. Modeling the electromagnetic force is particularly tricky because it is a nonlinear function of the actuated object's position and coil's current.

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Introduction: Non-pharmacological interventions are increasingly being acknowledged as valuable options to overcome or reduce functional problems in patients with Parkinson's disease. In the last decades, Nordic Walking was employed and investigated by rehabilitation specialists. Clinical trials on the effect of Nordic Walking on motor and non-motor Parkinson's disease symptoms are few, small, and heterogeneous for inclusion criteria and intervention protocols.

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Background: Scientific literature shows a high prevalence of Small Intestinal Bacterial Overgrowth (SIBO) in patients with Cystic Fibrosis (CF). The role of SIBO in nutritional status and gastrointestinal symptoms in CF is not known. Our aim was to study epidemiology and clinical impact of SIBO while assessing the efficacy of rifaximin in eradicating SIBO in CF patients.

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We address the optimal control of level sets associated with the solution of the normal flow equation. The problem consists in finding the normal velocity to the front described by a certain level set in such a way to minimize a given cost functional. First, the considered problem is shown to admit a solution on a suitable space of functions.

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Article Synopsis
  • Researchers used next-generation sequencing to study airway microbiota in cystic fibrosis (CF) patients, revealing insights into microbial gene functions and their relation to lung disease stages.
  • The study performed sputum shotgun metagenome sequencing on 12 CF patients, identifying key metabolic pathways related to bacterial movement, antibiotic resistance, and virulence genes in relation to pulmonary function.
  • Findings suggest that patients with severe CF have a microbiome enriched in genes that promote microbial colonization and resistance, indicating a link to multidrug-resistant communities in severe lung disease cases.
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