Photo-physical mechanism of near-IR femtosecond laser-induced refractive-index change in PMMA.

Micromodification in bulk undoped polymethylmethacrylate (PMMA) by single focused (numerical aperture (NA) = 0.25), 1030-nm 250-fs laser pump pulses was explored by pump self-transmittance; optical, 3D-scanning confocal photoluminescence (PL); Raman micro-spectroscopy; and optical polarimetric and interferometric microscopy. Starting from the threshold pulse energy  = 0.

Evaluation of the agronomic traits and correlation analysis of phenotypes of proso millet (Panicum miliaceum L.) germplasm in Kazakhstan.

Proso millet is a valuable short-term crop of universal use cultivated all over the world. However, due to the lack of genetic improvement, the yield of this crop does not provide stable in-come for farmers. The research is aimed to test proso millet germplasm of different geographical origin under different agro-climatic regions in Kazakhstan.

Ugi bisamides based on pyrrolyl-β-chlorovinylaldehyde and their unusual transformations.

By one-pot four- and three-component Ugi reactions involving convertible isocyanides and unexplored pyrrole-containing β-chlorovinylaldehyde, a small library of 20 bisamides with unusual behavior in post-Ugi transformations was prepared and characterized. Surprisingly, a well-documented approach to obtain peptide-containing carboxylic acids through acid hydrolysis of the convertible isocyanide moiety in the Ugi bisamides proceeded in an unexpected manner in our case, leading to the formation of derivatives of amides of heterylidenepyruvic acid. An optimized synthetic protocol for this transformation was elaborated and a plausible sequence involving the elimination of the 2-chloroacetamide moiety and the conversion of the β-chlorovinyl fragment into a vinyl one is provided.

Phosphorylation of (Ser 291) in the linker insert of Syk negatively regulates ITAM signaling in platelets.

Receptor-induced tyrosine phosphorylation of spleen tyrosine kinase (Syk) has been studied extensively in hematopoietic cells. Metabolic mapping and high-resolution mass spectrometry, however, indicate that one of the most frequently detected phosphorylation sites encompassed S297 (S291 in mice) located within the linker B region of Syk. It has been reported that Protein kinase C (PKC) phosphorylates Syk S297, thus influencing Syk activity.

[Outcomes of extended depth of focus intraocular lenses implantation].

Unlabelled: Extended depth of focus (EDOF) intraocular lenses (IOLs) are the latest IOL designs. In recent years, several models of EDOF IOLs have become available in Russia, two of which (Tecnis Symfony and Acrysof IQ Vivity) are implanted in our clinic. Comparative studies devoted to the results of implantation of the new EDOF IOLs are rare in the available literature.