[Necrotizing fasciitis--a clinical model of the department of public health: medicine of critical state].

The article reports the questions, which are associated with the interpretation of disease pathogenesis. The data are based on an analytical generalization of the follow-up study of 59 patients with necrotizing fasciitis in 2003-2011. The main component is stressed: disorders of microcirculation of superficial fascia as a result of thrombosis on basis of the hypercoagulation with outcome to necrosis, which was accompanied with POI syndrome, which manifested with severe form of sepsis (Hardaway theory) and can be considered as main cause of fatal outcome.

[Review of conservative replacement methods of the included minor defects of dentitions].

The paper reports the review of replacement methods of one absent tooth. The study was an assessment of prosthetic work in 275 patients with similar diagnosis. The aim of the study was to compare the indications for different fixed appliances with adhesive bonding on the example of schematic clinical situations.

[Cholangitis and biliary sepsis: problem and ways of solution].

The distinctions and interrelationship were established between acute cholangitis and biliary sepsis. Patients with hyperbilirubinemia were divided into four groups according to the developed criteria of inclusion and of using a new strategy of treatment for each group. It determined the result of treatment, i.

[Quantitative determination of the metabolite level in human urine by NMR 1H spectroscopy].

Conditions for registration of urinary NMR 1H spectra have been optimized in order to achieve maximal accuracy of quantitative analysis. Urinary samples from patients with acute pancreatitis have been investigated. Employment of NMR 1H spectroscopy is perspective for the development of new laboratory diagnostic methods.

[Application of exchangeable transhepatic frame stents in patients with posttraumatic strictures of the hepatic and common bile duct].

For the period from 2000 through 2007 there were 27 patients treated for lesions of extrahepatic bile ducts of different genesis. Since all the lesions were high, we have formed biliodigestive anastomoses on the exchangeable transhepatic drains by the method of Groetz-Saypol-Kurian. In a month after the operation and a standard management of the exchangeable transhepatic drains we departed from the classical technique and applied nonperforated drains.