Publications by authors named "A Isosalo"

The utilization of artificial intelligence (AI) is expanding significantly within medical research and, to some extent, in clinical practice. Deep learning (DL) applications, which use large convolutional neural networks (CNN), hold considerable potential, especially in optimizing radiological evaluations. However, training DL algorithms to clinical standards requires extensive datasets, and their processing is labor-intensive.

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Background: Digital breast tomosynthesis (DBT) has been widely adopted as a supplemental imaging modality for diagnostic evaluation of breast cancer and confirmation studies. In this study, a deep learning-based method for characterizing breast tissue patterns in DBT data is presented.

Methods: A set of 5388 2D image patches was produced from 230 right mediolateral oblique, 259 left mediolateral oblique, 18 right craniocaudal, and 15 left craniocaudal single-breast DBT studies, using slice-wise annotations of abnormalities and normal tissue.

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Background: Development of deep convolutional neural networks for breast cancer classification has taken significant steps towards clinical adoption. It is though unclear how the models perform for unseen data, and what is required to adapt them to different demographic populations. In this retrospective study, we adopt an openly available pre-trained mammography breast cancer multi-view classification model and evaluate it by utilizing an independent Finnish dataset.

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Article Synopsis
  • Magnetic resonance fingerprinting (MRF) is a technique that accelerates MRI data collection but typically falls short of creating contrast-weighted images needed for radiology.
  • This study aims to enhance MRF's clinical usefulness by using U-net models to synthesize high-quality contrast-weighted MR images from MRF quantitative data, employing various loss functions during training.
  • Results show that the synthetic images achieved high quality, with the best outcomes derived from a combination of loss functions, as assessed by radiologists using a 5-point Likert scale.
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