Publications by authors named "A Ishikawa"
Objectives: We aimed to evaluate the performance of the optic disc-macula distance to disc-diameter ratio (DM/DD) in qualitative and quantitative assessment of optic disc size.
Methods: In 300 apparently normal eyes, we determined the correlation between DM/DD and the planimetric disc area (DA) and evaluated the performance of DM/DD in discriminating between small and large discs. The ability of DM/DD to predict the actual DA was validated in a separate cohort of 200 eyes.
Article Synopsis
- This study examines genetic diversity, runs of homozygosity (ROH), and selection signatures in 11 chicken populations, focusing on native Japanese breeds compared to foreign ones.
- The Oh-Shamo breed showed the highest genetic diversity, while six native breeds exhibited moderate levels of diversity and ROH.
- Analysis grouped the populations into four clusters and identified seven key SNPs related to genetic variants affecting fear-related behavior, offering valuable insights for breeding and conservation efforts.
Gastric cancer (GC) is the third leading cause of cancer-related deaths in Japan, underscoring the urgent need for deeper insights into its pathogenesis. Spheroids provide a more realistic and versatile model for studying cancers and cancer stem cells (CSCs). While fructose-bisphosphate aldolase C (ALDOC) has been identified in colorectal cancer spheroids, its role in GC has remained largely unexplored.
View Article and Find Full Text PDFSharing of data archive of radiation exposure animal experiments in QST/NIRS and IES.
Radiat Prot Dosimetry
November 2024
Article Synopsis
- - The Institute for Radiological Science, QST, and IES have conducted significant animal experiments to analyze radiation risks related to life expectancy and cancer rates.
- - Due to economic, practical, and ethical challenges, there's a need to store data and biological samples from these experiments for future research and sharing.
- - QST/NIRS has created J-SHARE, an archive to store and promote collaboration on radiation biology research, and aims to integrate data and tissue specimens from IES to enhance knowledge on radiation risk assessment and protection.