Publications by authors named "A Invernizzi"

Background: We aimed to describe a 2-year outcome of eyes managed by practitioners benchmarked using a funnel plot by their frequency of treatment using vascular endothelial growth factor (VEGF) inhibitors for naive retinal vein occlusion (RVO).

Methods: A multicentre, international, observational study of 29 doctors in 12 countries managing 1110 eyes with RVO commencing VEGF inhibitors between 1 January 2012-2022 tracked in the Fight Retinal Blindness! registry.

Results: We identified 3 outlying 'intensive' practitioners (managing 350/1110 eyes [32%]), 22 'typical' practitioners (604/1110, [54%]) and 4 outlying 'relaxed' practitioners (156/1110, [14%]) with respective 24-month outcomes in Branch and Central RVO including the primary outcome, mean adjusted change in visual acuity (VA) in BRVO: +16.

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Background: In the aftermath of the World Trade Center (WTC) attack on 11 September 2001, rescue and recovery workers faced hazardous conditions and toxic agents. Prior research linked these exposures to adverse health effects, but mainly examined individual factors, overlooking complex mixture effects.

Methods: This study applies an exposomic approach encompassing the totality of responders' experience, defined as the WTC exposome.

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Article Synopsis
  • The study evaluates the clinical outcomes of cataract surgery in patients with cystoid macular edema (CMO) due to retinal vein occlusions (RVOs), comparing those who had surgery to matched individuals who did not.
  • Results showed a significant improvement in visual acuity (VA) for patients who underwent cataract extraction (+9.9 letters), while the control group experienced a decline (-2.4 letters) after 12 months.
  • Post-surgery, the eyes that had cataract surgery required more injections for treatment on average (5 injections) compared to the controls (4 injections), highlighting a possible increased need for ongoing care after surgery.
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Objective: To analyze longitudinal changes of retinal neovessels (NV) in eyes with proliferative diabetic retinopathy (PDR) after 3 monthly intravitreal injections (IVI) of ranibizumab by means of different imaging modalities, particularly focusing on optical coherence tomography (OCT) and OCT-angiography (OCT-A) features.

Methods: Prospective, monocentric study, Luigi Sacco Hospital, Milan. Consecutive patients with PDR were enrolled.

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Article Synopsis
  • - The survey, developed by the International Uveitis Study Group, aimed to assess how uveitis and retina specialists use current terminology and multimodal imaging (MMI) for diagnosing white dot syndromes (WDS).
  • - Out of 432 initial respondents, 263 completed the survey, revealing that most participants specialize in uveitis and utilize MMI, with nearly 90% using it for WDS diagnosis but showing varied usage of the term WDS.
  • - The findings suggest a strong consensus among specialists for redefining WDS based on anatomical location rather than the current clinical term, emphasizing MMI's role in enhancing diagnostic precision.
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