Publications by authors named "A Imrie"

Precise mosquito identification is integral to effective arbovirus surveillance. Nonetheless, the conventional morphological approach to identifying mosquito species is laborious, demands expertise and presents challenges when specimens are damaged. DNA barcoding offers a promising alternative, surmounting challenges inherent in morphological identification.

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Article Synopsis
  • Ross River virus (RRV) and Barmah Forest virus (BFV) are related viruses found in Australia and Papua New Guinea, showing evidence of convergent evolution in their genetic development.
  • Analysis of multiple genomes revealed that specific mutations in key proteins are important for their replication and interaction with host cells, indicating similarities in how both viruses adapt to their environments.
  • Although some mutations appear to have benefited their evolution, the overall selection pressures suggest that RRV and BFV have undergone purifying selection, maintaining stable functions during their replication in different hosts like mosquitoes and vertebrates.
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This study highlights the importance of human milk in providing anti-severe acute respiratory syndrome coronavirus 2 immunity to newborns. The highest protective activity of human milk against COVID-19 was found in colostrum from infected mothers. Neutralizing activity was associated with high levels of specific IgA.

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Mosquitoes harbor a wide diversity of microorganisms, including viruses that are human pathogens, or that are insect specific. We used metatranscriptomics, an unbiased high-throughput molecular approach, to describe the composition of viral and other microbial communities in six medically important mosquito species from across Western Australia: , , , , biotype , and . We identified 42 viral species, including 13 novel viruses, from 19 families.

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Sindbis virus (SINV) is a widely dispersed mosquito-borne alphavirus. Reports of Sindbis disease are largely restricted to northern Europe and South Africa. SINV is frequently sampled in Australian mosquito-based arbovirus surveillance programs, but human disease has rarely been reported.

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