Publications by authors named "A Ilchyshyn"

Article Synopsis
  • Erythroderma (exfoliative dermatitis) leads to significant metabolic changes, particularly an increase in energy expenditure.
  • This increase in total energy expenditure (TEE) is influenced by factors like basal metabolic rate, physical activity, and thermic effect of food.
  • The review discusses the mechanisms affecting energy balance in erythroderma and proposes dietary management strategies to address the condition's impact on health.
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Erythroderma (exfoliative dermatitis), first described by Von Hebra in 1868, manifests as a cutaneous inflammatory state, with associated skin barrier and metabolic dysfunctions. The annual incidence of erythroderma is estimated to be 1-2 per 100 000 population in Europe with a male preponderance. Erythroderma may present at birth, or may develop acutely or insidiously (due to progression of an underlying primary pathology, including malignancy).

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Background: Recessive forms of congenital ichthyosis encompass a group of rare inherited disorders of keratinization leading to dry, scaly skin. So far, 13 genes have been implicated, but there is a paucity of data on genotype-phenotype correlation in some populations.

Objectives: We compiled an English cohort of 146 individuals with recessive ichthyosis and assessed genotype-phenotype correlation.

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