Publications by authors named "A Iftimovici"
Article Synopsis
- The study investigates how early-adolescence prodromes in schizophrenia (SCZ) relate to social cognition deficits and sensorimotor impairments, comparing them to autism spectrum disorders (ASD).
- It involves four groups: ASD, SCZ with early-adolescence prodromes (under 15), SCZ with late-adolescence prodromes (over 15), and a control group, analyzing their social cognition and neurological soft signs (NSS).
- Findings indicate that SCZ with early prodromes show similar social cognition impairments as those with ASD, highlighting that age of prodrome onset plays a critical role in understanding SCZ subgroups rather than just the onset of psychosis.
Objective: This study was undertaken to characterize the clinical and genetic features of patients with 22q11.2 deletion syndrome (22q11.2DS) and generalized epilepsy compared with 22q11.
View Article and Find Full Text PDFBackground: Cognitive impairment constitutes a prevailing issue in the schizophrenia spectrum, severely impacting patients' functional outcomes. A global cognitive score, sensitive to the stages of the spectrum, would benefit the exploration of potential factors involved in the cognitive decline.
Methods: First, we performed principal component analysis on cognitive scores from 768 individuals across the schizophrenia spectrum, including first-degree relatives of patients, individuals at ultra-high risk, who had a first-episode psychosis, and chronic schizophrenia patients, alongside 124 healthy controls.
Background: Treatment resistance is a major challenge in psychiatric disorders. Early detection of potential future resistance would improve prognosis by reducing the delay to appropriate treatment adjustment and recovery. Here, we sought to determine whether neurodevelopmental markers can predict therapeutic response.
View Article and Find Full Text PDFBackground: Psychiatric disorders often emerge during adolescence or young adulthood, leading to significant disability among youth. The transition from Child and Adolescent Mental Health Services (CAMHS) to Adult Mental Health Services (AMHS) is critical for individuals experiencing emerging psychopathology, with delayed access to care negatively impacting long-term outcomes. Accessing mental health services for adolescents and young adults is often complex and delayed due to challenges in service visibility, accessibility and appropriateness.
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