Publications by authors named "A Idil"
Article Synopsis
- Spatially selective vagus nerve stimulation (sVNS) shows potential for improving treatment for heart disease by targeting specific nerve fibers to minimize side effects.
- Research on pigs found that cardiac afferent and efferent fibers are significantly separated in the vagus nerve, allowing for more precise neuromodulation during sVNS.
- This understanding may lead to more effective treatments that can reduce heart rates without triggering unwanted reflexes, making sVNS a valuable option for managing heart disease.
Article Synopsis
- The study aimed to evaluate reading performance in patients with mild to moderate primary open-angle glaucoma (POAG) and explore its correlation with visual field measurements, microperimetry, and optical coherence tomography (OCT) parameters.
- Researchers compared the reading abilities of 30 POAG patients to 21 age-matched controls using various testing methods, and assessed the relationship between reading metrics and glaucoma severity indicators.
- Results showed significant links between maximum reading speed (MRS) and specific OCT measurements, with worse reading performance in patients’ poorer eye, while other visual field measures did not correlate with reading ability.
A Report on Children with CEP290 Mutation, Vision Loss, and Developmental Delay.
Beyoglu Eye J
September 2023
Mutations in CEP290, which encodes a centrosomal protein, cause Joubert syndrome, retinal dystrophy, and several other manifestations. Retinal dystrophy related to CEP290 mutation (Leber's congenital amaurosis type 10) presents with a severe visual impairment from birth, wandering eye movements, and oculodigital reflex. Fundus examination may initially be normal, but varying degrees of retinal pigmentation can be detected over time.
View Article and Find Full Text PDFPurpose: The purpose of the study is to evaluate the low vision rehabilitation methods and to investigate the effect of visual rehabilitation on quality of life in patients with low vision due to geographic atrophy from age-related macular degeneration (ARMD).
Methods: The better-seeing eye of 78 patients with geographic atrophy due to ARMD were included in the study. Sociodemographic characteristics, ophthalmological examination findings, and preferred low vision aids for near and distant were recorded.
Electrical neurostimulation is effective in the treatment of neurological disorders, but associated recording artefacts generally limit its applications to open-loop stimuli. Real-time and continuous closed-loop control of brain activity can, however, be achieved by pairing concurrent electrical recordings and optogenetics. Here we show that closed-loop optogenetic stimulation with excitatory opsins enables the precise manipulation of neural dynamics in brain slices from transgenic mice and in anaesthetized non-human primates.
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