Impact of Vaccination on the Course and Outcome of COVID-19 in Patients with Multimorbidity.

Vaccination is the most cost-effective method of preventing COVID-19; however, data on its effect on patients with multimorbidity is limited. The aim was to evaluate the effect of vaccination against new coronavirus infection (NCI) in patients with multimorbid pathology in hospital treatment on the outcome of COVID-19 disease. An analysis was carried out of 1832 records of patients in one of the COVID-19 hospitals in Moscow for 2020-2022.

Healthcare Workers' Acceptance of COVID-19 Vaccination in Russia.

During the COVID-19 pandemic, the problem of the population's adherence to vaccination has become significantly aggravated around the world. This study is aimed at evaluating healthcare workers' (HCWs) acceptance of COVID-19 vaccination in Russia. A cross-sectional multicenter study was carried out by interviewing HCWs in Russia using an electronic questionnaire and snowball sampling.

ASSESSMENT OF ATTITUDES TOWARDS IMMUNIZATION IN DIFFERENT GROUPS OF POPULATION OF THE RUSSIAN FEDERATION.

Aim: The study the attitude of population towards the necessity of vaccination.

Materials And Methods: The survey about the attitude towards vaccination among different groups of population was held. In total there were 1209 respondents: 1031 students of medical, humanitarian and tech- nical universities and 178 parents of children under 2.

[UNIVERSALITY OF CHANGES IN EPIDEMIC PROCESS MANIFESTATIONS OF ANTHROPONOSIS INFECTIONS IN RECENT DECADES].

Aim: Detection of main regularities of anthroponosis infections with various degrees of manageability and factors that determine them in contemporary social-demographic conditions.

Materials And Methods: A comparative retrospective epidemiologic analysis of morbidity of the population with viral hepatitis A, Sonnei and Flexneri shigellae, rotavirus infection, pertussis, diphtheria, varicella, rubella, pneumococcal infection and possible risk factors by 47 European countries and territories of Russian Federation was carried out, the maximum depth of search was 89 years.

Results: Common epidemiologic regularities were shown to be characteristic for anthroponosis infection regardless of the degree of their manageability, that are manifested by the presence of large and small cycles in the multi-year dynamics of morbidity changes of age-related morbidity structure and its pronounced territorial non-uniformity.

[Clinical epidemiology: theory and practice].

The paper gives the definition, goal, and objectives of clinical epidemiology. The latter is shown to be an epidemiology section that makes it possible to elaborate evidence-based standards for diagnosis, treatment, and prevention and to select a respective algorithm of actions for each specific clinical case. Randomized controlled trials are the gold standard for obtaining evidence.