[Methods of statistical analysis in differential diagnostics of the degree of brain glioma anaplasia during preoperative stage].

The authors proposed a possible preoperative diagnostics of the degree of supratentorial brain gliom anaplasia using statistical analysis methods. It relies on a complex examination of 934 patients with I-IV degree anaplasias, which had been treated in the Institute of Neurosurgery from 1990 to 2004. The use of statistical analysis methods for differential diagnostics of the degree of brain gliom anaplasia may optimize a diagnostic algorithm, increase reliability of obtained data and in some cases avoid carrying out irrational operative intrusions.

[Clinico-morphologic evaluation of susceptibility of glioblastoma to antiblastic therapy].

Pathomorphology of a cerebral glioblastoma in 82 patients was studied. The most pronounced regressive changes in the glioblastoma occurred under the influence of a complex of antiblastic treatment, including polychemo- and immunotherapy, radiation therapy. A high degree of damaging effect on a glioblastoma tissue correlated with the longest lifetime of the patients--(22.

[Efficacy of chemotherapy and immunochemotherapy in neuro-oncologic patients of various blood groups (ABO system)].

The efficacy of postoperative chemo- and immunochemotherapy was analysed according to the survival period from study of the catamnesis of patients who underwent operation for malignant (III-IV degree malignancy) gliomas. In analysing the efficacy of various schedules of combined treatment, the authors took into consideration the patients AB0 blood group because it is known that many antineoplastic antibiotics contain structures which are marked by cross reaction with the ABH isoantigens. The results of the study showed that the use of polychemotherapy and levamisole in neuro-oncological patients with A(II) and AB(IV) blood groups is promising.