Publications by authors named "A I Zinchenko"

IgA1 protease is one of the virulence factors of , and other pathogens causing bacterial meningitis. The aim of this research is to create recombinant proteins based on fragments of the mature IgA1 protease A-P from serogroup B strain H44/76. These proteins are potential components of an antimeningococcal vaccine for protection against infections caused by pathogenic strains of and other bacteria producing serine-type IgA1 proteases.

View Article and Find Full Text PDF

There is evidence that congenitally blind individuals possess superior auditory perceptual skills compared to sighted people. However, relatively little is known about the auditory-specific cortical correlates of spatial attention in the blind and how task-irrelevant emotional stimulus features could further modulate such neural processes. This study tested blind and sighted participants in a challenging auditory discrimination task.

View Article and Find Full Text PDF

Transcranial Direct Current Stimulation (tDCS) is a non-invasive brain stimulation technique used to modulates cortical brain activity. However, its effects on brain metabolites within the dorsolateral prefrontal cortex (DLPFC), a crucial area targeted for brain stimulation in mental disorders, remain unclear. This study aimed to investigate whether prefrontal tDCS over the left and right DLPFC modulates levels of key metabolites, including gamma-aminobutyric acid (GABA), glutamate (Glu), glutamine/glutamate (Glx), N-acetylaspartate (NAA), near to the target region and to explore potential sex-specific effects on these metabolite concentrations.

View Article and Find Full Text PDF
Article Synopsis
  • Hydrothermal treatment of fishery waste-derived chitin (CT) and chitosan (CS) was conducted to create hydrochar adsorbents aimed at removing environmentally concerning pharmaceuticals.
  • The study found that lower-temperature CS hydrochars had better adsorption capabilities for pharmaceuticals with carboxyl groups due to electrostatic interactions, while higher temperatures led to reduced adsorption efficiencies due to a decrease in available amine sites.
  • Overall, this research highlights the dual benefit of utilizing marine waste for creating effective adsorbents while also addressing pollution issues from pharmaceuticals.
View Article and Find Full Text PDF

Recently, cellulose and other biomass nanofibers (NFs) have been increasingly utilized in the design of sustainable materials for environmental, biomedical, and other applications. However, the past literature lacks a comparison of the macromolecular and nanofibrous states of biopolymers in various materials, and the advantages and limitations of using nanofibers (NF) instead of conventional polymers are poorly understood. To address this question, hydrogels based on interpolyelectrolyte complexes (IPECs) between carboxymethyl cellulose nanofibers (CMCNFs) and chitosan (CS) were prepared by ele+ctrostatic cross-linking and compared with the hydrogels of carboxymethyl cellulose (CMC) and CS biopolymers.

View Article and Find Full Text PDF