Prostate cancer remains a lethal disease for many men. Knowledge of genetic contributions to this condition has increasingly been used in its management. In this narrative review, we summarize various genetic alterations and syndromes associated with prostate cancer, including hereditary breast and ovarian cancer syndrome, Lynch syndrome, and hereditary prostate cancer, among others.
View Article and Find Full Text PDFProbl Sotsialnoi Gig Zdravookhranenniiai Istor Med
October 2024
The aim of this study was to examine the level of salt consumption among various population groups in Moscow. The study was conducted using the 24-hour dietary recall method (24hDR) and the food frequency questionnaire (FFQ) over the course of one year. The results showed that 49.
View Article and Find Full Text PDFA robust route to produce poly(methyl methacrylate) (pMMA) hybrid latex particles (radius ∼250 nm) that are selectively "armored" with silica nanoparticles (radius 12.5 nm) through addition of vinyltriethoxysilane was previously shown ( 2018, 528, 289-300).Depending on synthesis conditions, the extent of nanoparticle attachment could be varied; however, the mechanism behind this attachment during latex growth remained unclear.
View Article and Find Full Text PDFHypothesis: Nano-scale dynamics of self-assembled therapeutics play a large role in their biological function. However, assessment of such dynamics remains absent from conventional pharmaceutical characterization. We hypothesize that time-resolved small-angle neutron scattering (TR-SANS) can reveal their kinetic properties.
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