High-fat diet protects the blood-brain barrier in an Alzheimer's disease mouse model.

Type 2 diabetes (T2D) is associated with increased risk of Alzheimer's disease (AD). There is evidence for impaired blood-brain barrier (BBB) in both diseases, but its role in the interplay between them is not clear. Here, we investigated the effects of high-fat diet (HFD), a model for T2D, on the Tg2576 mouse model of AD, in regard to BBB function.

[Treatment of external intestinal fistulas in children].

The experience with the treatment of 132 children with the external intestinal fistulas is summarized. In 28, the fistulas closed under the influence of conservative therapy. Operated on were 44 children.