Success of minimally invasive single-gland exploration using the quick intraoperative parathyroid assay.

Objective: Using accurate localization techniques and the quick intra-operative parathyroid assay (QPTH), surgery for primary hyperparathyroidism due to a solitary adenoma has moved from the traditional wide bilateral neck exploration to more limited approaches such as minimally invasive single-gland exploration (MISGE) and minimally invasive radio-guided parathyroidectomy (MIRP). This study investigated whether the MISGE could take the place of MIRP with the help of the QPTH.

Design: From 2007 to 2009, 56 patients with primary hyperparathyroidism were studied.