Objective: The aerolysin (aerA) is a virulence indicator used to identify the pathogenicity of the strain. Targeting a pathogen's crucial virulence gene for detection is essential, as it determines the potential threat to the host. This study aimed to develop a gold nanoparticle (AuNP) probe for detecting the gene A in among field samples.
View Article and Find Full Text PDFInfections remain a common complication in patients with multiple myeloma (MM) and are associated with morbidity and mortality. A risk score to predict the probability of early severe infection could help to identify the patients that would benefit from preventive measures. We undertook a post hoc analysis of infections in four clinical trials from the Spanish Myeloma Group, involving a total of 1347 patients (847 transplant candidates).
View Article and Find Full Text PDFThis study is the first investigation of parasites and other pathogens present in Sunda leopard cats () in Aborlan, Palawan, Philippines. With the nature of wild carnivore sampling, four (4) wild Sunda leopard cats were captured in Aborlan, Palawan, Philippines for a period of nine (9) months. Of these, three (3) were considered for blood and fecal examination due to the poor condition of one animal.
View Article and Find Full Text PDFCurr Treat Options Oncol
April 2021
Hematopoietic stem cell transplantation (HSCT) is considered, since 1957, a potentially curative therapeutic option for many hemopathies. Although it is an aggressive procedure, improvements in transplantation techniques and supportive strategies have markedly decreased treatment-related mortality, and the prevalence of HSCT survivors is expected to exceed half a million by 2030. At the same time, there is a growing awareness of the potentially negative effects of HSCT-related therapies on the cardiovascular (CV) system, and HSCT survivors constitute a population at high cardiovascular (CV) risk.
View Article and Find Full Text PDFWe examined the vertical stratification of forest wildlife, from the ground up to the canopy layer, within a 2-hectare permanent plot of lowland evergreen rainforest on the Mt. Makiling Forest Reserve. Our aim was to determine the species richness of the different forest layers and evaluate their ecosystem services.
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