[Prognostic factors in bladder cancer].

DNA distribution was studied in tumor cells of 54 patients with bladder cancer. Diploid and aneuploid distributions were recorded in 34 and 20 cases, respectively. Aneuploid DNA proved to be a negative prognostic factor as 5-year survival of such patients made up 48.

[The prognostic aspects of the morphological signs of bladder cancer].

A clinico-morphological study of 150 bladder tumours showed significant dependence of bladder carcinoma prognosis on some morphological indices most important of which were the grade of malignancy, histological type and deepness of growth and spread along the lymphatic and blood vessels. Likewise, nuclear polymorphism and hyperchromasia, mitotic figure number, atypical mitosis have a direct connection with prognosis, but they are an integral part of malignancy grade determination and do not play an independent role. Nucleolar organizer zone may serve as an additional criterium of neoplasm biological activity, in particular, its role is important in differential diagnosis of bladder transitional cell carcinoma I and benign processes or transitional papilloma.

[The prognostic value of flow cytometry in prostatic cancer].

DNA quantitation by flow cytometry was made in 36 patients with morphologically diagnosed prostatic cancer (PC) in stage II, III and IV (4, 14 and 18 patients, respectively). All the patients received adequate treatment. Aneuploid tumours were found in 25 patients (group 1), diploid ones in 11 patients (group 2).