Publications by authors named "A I Mikhaylov"

Irumamycin (Iru) is a complex polyketide with pronounced antifungal activity produced by a type I polyketide (PKS) synthase. Iru features a unique hemiketal ring and an epoxide group, making its biosynthesis and the structural diversity of related compounds particularly intriguing. In this study, we performed a detailed analysis of the biosynthetic gene cluster (BGC) to uncover the mechanisms underlying Iru formation.

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In this manuscript, we investigate the memristor-based implementation of neuronal ion channels in a mathematical model and an experimental circuit for a neuronal oscillator. We used a FitzHugh-Nagumo equation system describing neuronal excitability. Non-linearities introduced by the voltage-gated ion channels were modeled using memristive devices.

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Article Synopsis
  • Social media has both benefits, like easy communication and information sharing, and drawbacks, particularly the prevalence of hate speech.
  • The study focuses on using a TF-IDF approach and various classifiers to automatically detect hate speech across three different datasets.
  • Several machine learning methods, including logistic regression, neural networks, and random forests, were employed, achieving over 99% accuracy in identifying hate speech.
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