Publications by authors named "A I Koyanagi"

Article Synopsis
  • The study aimed to categorize tumor-associated stroma (TAS) in triple-negative breast cancer (TNBC) to reflect its biological behavior.
  • Researchers analyzed 120 TNBC cases, classifying TAS into mature stroma (MS) and immature stroma (IS), finding that MS was more common and associated with higher tumor-infiltrating lymphocytes (TILs).
  • Results indicated that IS was linked to poorer progression-free and overall survival rates, highlighting the significance of TAS characteristics in TNBC prognosis and the need for further investigation.
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Article Synopsis
  • * Both male and female schizophrenia patients faced higher risks of all-cause mortality, suicide, and natural causes, but no significant differences were found between the sexes in these risks.
  • * Young females (<40) showed a notably higher mortality risk compared to older females, while males faced a much greater risk of dying from neurological disorders than females, indicating a need for better healthcare interventions.
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Objective: To identify the COVID-19 pandemic impact on well-being/mental health, coping strategies, and risk factors in adolescents worldwide.

Method: This study was based on an anonymous online multi-national/multi-language survey in the general population (representative/weighted non-representative samples, 14-17 years of age), measuring change in well-being (World Health Organization-Five Well-Being Index [WHO-5]/range = 0-100) and psychopathology (validated composite P-score/range = 0-100), WHO-5 <50 and <29, pre- vs during COVID-19 pandemic (April 26, 2020-June 26, 2022). Coping strategies and 9 a priori- defined individual/cumulative risk factors were measured.

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Objective: Although thyroid disease is a common condition, there is limited research examining the prevalence of thyroid disease over a long period of time, including both before and during the COVID-19 pandemic. Therefore, we aimed to investigate sociodemographic aspects that might be associated with thyroid disease and how its prevalence has varied during the pandemic.

Methods: We assessed the prevalence of thyroid disease among Korean adults by using data from the Korea National Health and Nutrition Examination Survey from 1998 to 2021.

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Background: Worldwide, cardiovascular diseases are the primary cause of death, with hypertension as a key contributor. In 2019, cardiovascular diseases led to 17.9 million deaths, predicted to reach 23 million by 2030.

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