[Pancreaticoduodenectomy combined with multivisceral resections].

Locally advanced tumors of the stomach, colon and hepatopancreatobiliary zone comprise more than 20% of all cancers. Treatment of these patients is difficult, since tumors have complications in more than 70% of cases. Appropriate treatment poses difficulties due to functional state of these patients.

[Repeated liver resections for recurrent intrahepatic cholangiocarcinoma].

Objective: To evaluate the safety and advisability of repeated liver resection (RLR) for recurrent intrahepatic cholangiocarcinoma (ICC).

Material And Methods: The results of RLR for ICC recurrence (=10) were retrospectively analyzed between 1999 and 2023. The control group consisted of patients undergoing primary liver resection for ICC (=195).

Surgical treatment and prognostic factors in perihilar tumors.

Objective: To study the results of surgical treatment in patients with perihilar tumors.

Material And Methods: We analyzed 98 patients with perihilar tumors who underwent surgery.

Results: We prefer percutaneous transhepatic biliary drainage (=58) for jaundice.

Cytological Analysis of Crossover Frequency and Distribution in Male Meiosis of Cardueline Finches (Fringillidae, Aves).

Meiotic recombination is an important source of genetic diversity. Using immunolocalization of several meiotic proteins at the spreads of male pachytene cells, we estimated the number of recombination nodules per cell and their distribution along the macrochromosome 1 of the , , , and . The macrochromosomes of the two former species have metapolycentromeres, composed of several centromeric domains.

Electrostatic effects on water-soluble fullerene derivatives interaction with cytochrome c and cytochrome c oxidase.

Water-soluble fullerene derivatives are good candidates for various biological applications such as anticancer or antimicrobial therapy, cytoprotection, enzyme inhibition, and many others. Their toxicity, both in tissue culture and in vivo, is a critical characteristic for the development and restriction of these applications. The effects of six water-soluble cationic and anionic polysubstituted fullerene derivatives on cytochrome c oxidase activity in rat brain mitochondria and the possibility of cytochrome c binding were studied.