L-Cysteine/Silver Nitrate/Iodate Anions System: Peculiarities of Supramolecular Gel Formation with and Without Visible-Light Exposure.

In this study, novel anion photo-responsive supramolecular hydrogels based on cysteine-silver sol (CSS) and iodate anions (IO) were prepared. The peculiarities of the self-assembly process of gel formation in the dark and under visible-light exposure were studied using a complex of modern physico-chemical methods of analysis, including viscosimetry, UV spectroscopy, dynamic light scattering, electrophoretic light scattering, scanning electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray photoelectron spectroscopy. In the dark phase, the formation of weak snot-like gels takes place in a quite narrow IO ion concentration range.

Large Language Model for Automating the Analysis of Cryoprotectants.

The rapid expansion of scientific literature necessitates developing efficient data extraction and analysis methods. This study presents an innovative approach to automating the extraction of cryoprotectant information from scientific publications using a generative pretrained transformer (GPT) model integrated with a Telegram bot interface. Our system processes and analyzes scientific articles to identify and extract relevant data on cryoprotectants and bacteria, significantly reducing the time required for researchers to gather essential information.

Characterization of the binding of the globular domains of the complement component C1q to phosphatidylserine.

C1q, the key component of the classical pathway of the Complement system, is known for its vast functional activity including clearance of apoptotic cells. The binding of C1q to apoptotic blebs occurs via an interaction with the phosphatidylserine externalized on the cell surface. In this study, we characterized the interaction between C1q and phosphatidylserine, with emphasis on the structure of the phosphatidylserine-binding site within the globular domains of C1q and the nature of binding of C1q with phosphatidylserine, using both in vitro and in silico methods.