Publications by authors named "A I Iartsev"

The aim of the study was to compare outer retinal layers in primary open-angle glaucoma (POAG) using spectral-domain optical coherence tomography (OCT). 15 patients (27 eyes) and 16 normal subjects (32 eyes) were examined. Patients were examined using OCT Spectralis ("Heidelberg Engineering", Germany) in order to analyze outer retinal layers and evaluate beta-zone extent.

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Comparative analysis of retinal structure was performed in patients with POAG and control healthy group using spectral OCT and histology. An apparent similarity of tomographic and histological patterns of retinal changes was found in patients with POAG. These results make OCT potentially appropriate method for vital examination of retinal structure in glaucomatous eyes including early stages of the disease.

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The regulatory function of the processes involving free radicals known to maintain cellular vital activity and their role as an intermediate stage of many vitally important enzymatic reactions attract the attention of researchers interested in the mechanisms of production and inactivation of free radicals. Investigations into prooxidant and antioxidant systems along with evaluation of the intensity of free-radical oxidation make it possible to resolve many problems including elucidation of dynamic activity of pathological process, prognosis of various pathological conditions, and the choice of possible methods for the correction of prooxidant/antioxidant balance in patients with ENT diseases. The development of algorithms and methods for the assessment of parameters of activity of the prooxidant system allows for their stage by stage measurement and evaluation.

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Difference spectra of hematoporphyrin excited by intense 300 is laser pulse were studied at various delay times. It was found that under two photon excitations very quick (approximately 1 ps) formation of photoproduct took place. Changes of the difference spectra connected with evolution of the photoproduct were observed.

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