[The assessment of a role of muramyl peptides in the treatment of patients with aggressive form of periodontitis].

The Aim Of The Study: Was to determine the effect of the drug based on the composition of muramyl peptides isolated from the cell walls of gram-negative bacteria on the production of α-defensins and the detectability of in patients with an aggressive form of periodontitis.

Material And Methods: 60 patients aged 28 to 40 years with an aggressive form of periodontitis were randomized into two equal groups, the main and control. In both groups, patients were removed dental deposits and taught the rules of oral hygiene, followed by three-fold control.

[Antibacterial effect of a non-specific immunomodulator based on muramilpeptides in chronic periodontitis].

The Aim Of The Study: Was to investigate the efficacy of immunomodulatory drug based on muramilpeptides for treatment of chronic generalized periodontitis.

Materials And Methods: The study group comprised 20 patients aged 25 to 64 with severe chronic periodontal disease. Periodontal pockets content was inoculated for specific microbial pathogens before and after treatment.

[Classification of periodontal and peri-implant tissues diseases (Euro-Perio, 2018). Advantages and inconveniences].

The article presents the «Classification of periodontal diseases and the state of perimplant tissues», adopted at the international Congress Euro-Perio-9 in 2018. The advantages and disadvantages of this systematics in comparison with the previous ones and with the classification currently adopted in the Russian Federation are noted.

[Clinical effectiveness of an immunomodulatory drug based on a muramylpeptide composition in the treatment of patients with chronic generalized periodontitis].

The Aim Of The Study: To assess the efficacy of an immunomodulatory drug based on a muramylpeptide composition in the treatment of patients with chronic generalized periodontitis.

Materials And Methods: The study comprised 40 patients with chronic generalized periodontitis. In controls the treatment consisted in oral hygiene instructions, professional oral hygiene procedures and root scalling while in main study group the conventional treatment protocol was combined with intramuscular injections of muramylpeptide composition.

[Orthodontic treatment of a patient with a thin gingival biotype and malocclusion].

Description of the clinical case of the patient with narrowing and deformation of the dentition of the upper and lower jaw and crowded teeth in the frontal part of the lower jaw in combination with a thin gingival biotype. The combined use of diagnostic methods: colorimetric probe, ultrasonic scanning and cone-beam computed tomography, followed by computer 3D-modeling of the treatment plan made it possible to competently plan and implement orthodontic treatment of the patient without complications from periodontal tissues. Combined application of colorimetric probe, ultrasonic and cone-beam computed tomography methods with digital 3D-modeling of the treatment plan allowed to plan and carry out orthodontic treatment of a patient with a thin gingival biotype without periodontal complications.