Publications by authors named "A I Frias"
Early recognition of acute kidney injury is essential to prevent progression to chronic kidney disease. We present the case of a 19-year-old man with multiple emergency department visits for fatigue, abdominal pain, and intermittent dark urine. Upon admission, he had pancytopenia with elements suggestive of hemolysis and acute kidney injury.
View Article and Find Full Text PDFPanic disorder is more frequent in women than in men. In women, vulnerability to panic is enhanced during the late luteal phase of the menstrual cycle. At this time secretion of progesterone and its neuroactive metabolite allopregnanolone (ALLO), which acts as a positive allosteric modulator of the actions of GABA at GABA receptors, decline sharply.
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- - The study examines how the estrous cycle affects the responses of female mice to carbon monoxide (CO), focusing on behaviors, brain chemistry, and physiological changes.
- - While all phases of the estrous cycle resulted in similar escape behaviors in response to CO, the ventilation and metabolic responses varied, notably showing higher ventilation and lower body temperature during hypercapnia.
- - The results indicate hypercapnia triggers panic-like behaviors in female mice and influences their hormone levels, but the phase of the estrous cycle does not alter the behavioral response to CO exposure.
Article Synopsis
- * In a study with 55 pregnant smokers, vitamin C improved umbilical blood flow compared to a placebo, bringing levels closer to those of nonsmokers.
- * RNA-sequencing results indicated that vitamin C altered gene expression related to vascular and cardiac development, hinting at its potential benefits for baby health in situations of prenatal nicotine exposure.
Article Synopsis
- The study focused on the effects of Impella malrotation on patients in cardiogenic shock, identifying the malrotation in 36% of cases.
- Findings indicated that those with malrotation experienced significantly worse pulmonary pressures, higher right atrial pressure, and elevated serum lactate levels compared to those without malrotation.
- The conclusions suggest that Impella malrotation leads to suboptimal left ventricular unloading and aggravated pulmonary and right ventricular conditions, though major adverse outcomes did not significantly differ.